Transcriptional properties of mammalian Elongin A and its role in stress response.
Kawauchi, J., Inoue, M., Fukuda, M., Uchida, Y., Yasukawa, T., Conaway, R.C., Conaway, J.W., Aso, T., and Kitajima, S.
J. Biol. Chem. 288 24302-24315 2013-
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Transcriptional elongation factor Elongin A regulates retinoic acid-induced gene expression during neuronal differentiation.
Yasukawa, T., Bhatt, S., Takeuchi, T., Kawauchi, J., Takahashi, H., Tsutsui, A., Muraoka, T., Inoue, M., Tsuda, M., Kitajima, S., Conaway, R.C., Conaway, J.W., Trainor, P.A., and Aso, T.
Cell Rep. 2 1129-1136 2012-
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Degradation of p21Cip1 through APC/CCdc20 mediated ubiquitylation is inhibited by cyclin dependent kinase 2 in cardiomyocytes.
Yamada, K., Tamamori-Adachi, M., Goto, I., Iizuka, M., Yasukawa, T., Aso, T., Okazaki, T., and Kitajima, S.
J. Biol. Chem. 286 44057-44066 2011-
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Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1.
Yasukawa, T., Kamura, T., Kitajima, S., Conaway, R.C., Conaway, J.W., and Aso, T.
EMBO J. 27 3256-3266 2008-
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Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A.
Miyata, K., Yasukawa, T., Fukuda, M., Takeuchi, T., Yamazaki, K., Sakumi, K., Tamamori-Adachi, M., Ohnishi, Y., Ohtsuki, Y., Nakabeppu, Y., Kitajima, S., Onishi, S., and Aso, T.
Cell Death Differ. 14 716-726 2007-
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Functional characterization of a mammalian transcription factor, Elongin A.
Yasukawa, T., Sugimura, K., Fukuda, M., Yamazaki, K., Kitajima, S., Okumura, K., and Aso, T.
Biochem. Biophys. Res. Commun. 352 237-243 2007-
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Ternary complex formation of pVHL, elongin B and elongin C visualized in living cells by a FRET-FLIM technique.
Kinoshita, K., Goryo, K., Takada, M., Tomokuni, Y, Aso, T., Okuda, H., Shuin, T., Fukumura, H., and Sogawa, K.
FEBS J. 274 5567-5575 2007-
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Identification of EloA-BP1, a novel Elongin A binding protein with an exonuclease homology domain.
Tamura, K., Miyata, K., Sugahara, K., Onishi, S., Shuin, T., and Aso, T.
Biochem. Biophys. Res. Commun. (276) 189-195 2003-
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Mammalian Elongin A is not essential for cell viability but is required for proper cell-cycle progression with limited alteration of gene expression.
Yamazaki, K., Aso, T., Ohnishi, Y., Ohno, M., Tamura, K., Shuin, T., Kitajima, S., and Nakabeppu, Y.
J. Biol. Chem. 278 13585-13589 2003-
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Identification and biochemical characterization of a novel transcription elongation factor, Elongin A3.
Yamazaki, K., Guo, L., Sugahara, K., Zhang, C., Enzan, H., Nakabeppu, Y., Kitajima, S., and Aso, T.
J. Biol. Chem. 277 26444-26451 2002-
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Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response.
Zhang, C., Yong, C., Adachi, M.T., Oshiro, S., Aso, T., Kaufman, R.J., and Kitajima, S.
J. Biol. Chem. 276 35867-35874 2001-
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C-Jun NH2-terminal kinase and transcriptional repressor ATF3/LRF-1 is activated through endoplasmic reticulum stress and implicated in human vascular endothelial cell death by homocysteine.
Zhang, C., Kawauchi, J., Adachi, M.T., Hashimoto, Y., Oshiro, S., Aso, T., and Kitajima, S.
Biochem. Biophys. Res. Commun. 289 718-724 2001-
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Drosophila von Hippel-Lindau tumor suppressor complex possesses E3 ubiquitin ligase activity.
Aso, T., Yamazaki, K., Aigaki, T., and Kitajima, S.
Biochem. Biophys. Res. Commun. (276) 355-361 2000-
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Homocysteine-responsive ATF3 gene expression in human vascular endothelial cells: signal transduction pathway and promoter responsive element.
Cai, Y., Zhang, C., Nawa, T., Aso, T., Tanaka, M., Oshiro, S., Ichijo, H., and Kitajima, S.
Blood 96 2140-2148 2000-
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Identification and characterization of Elongin A2, a new member of an Elongin family of transcription elongation factors, specifically expressed in the testis.
Aso, T., Yamazaki, K., Amimoto, K., Kuroiwa, A., Higashi, H., Matsuda, Y., Kitajima, S., and Hatakeyama, M.
J. Biol. Chem. 275 6546-6552 2000-
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Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau tumor suppressor protein.
Ohh, M., Takagi, Y., Aso, T., Stebbins, C.E., Pavletich, N.P., Zbar, B., Conaway, R.C., Conaway, J.W., and Kaelin, W.G.
J. Clin. Invest. 104 1583-1591 1999-
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Structural organization and chromosome location of the mouse Elongin A gene (Tceb3).
Aso, T., Amimoto, K., Takebayashi, K., Okumura, K., and Hatakeyama, M.
Cytogenet. Cell Genet. 86 259-262 1999-
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Physical interaction and functional antagonism between the RNA polymerase II elongation factor ELL and p53.
Shinobu, N., Maeda, T., Aso, T., Ito, T., Kondo, T., Koike, K., and Hatakeyama, M.
J. Biol. Chem. 274 17003-17010 1999-
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Molecular cloning of DNAs encoding the regulatory subunits of Elongin from Saccharomyces cerevisiae and Drosophila melanogaster.
Aso, T., and Conrad, M.N.
Biochem. Biophys. Res. Commun. 241 334-340 1997-
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Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators.
Pan, G., Aso, T., and Greenblatt, J.
J. Biol. Chem. 272 24563-24571 1997-
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The inducible elongin A elongation activation domain: structure, function and interaction with the elongin BC complex.
Aso, T., Haque, D., Barstead, R.J., Conaway, R.C., and Conaway, J.W.
EMBO J. 15 5557-5566 1996-
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Transcription syndromes and the role of RNA polymerase II general transcription factors in human disease.
Aso, T., Shilatifard, A., Conaway, J.W., and Conaway, R.C.
J. Clin. Invest. 97 1561-1569 1996-
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A human cDNA encoding the 110-kDa A subunit of RNA polymerase II transcription factor elongin.
Aso, T., Haque, D., Fukudome, K., Brower, C.S., Conaway, J.W. and Conaway, R.C.
Gene 168 277-278 1996-
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Elongin (SIII) : A multisubunit regulator of elongation by RNA polymerase II.
Aso, T., Lane, W.S., Conaway, J.W., and Conaway, R.C.
Science 269 1439-1443 1995-
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Inhibition of transcription elongation by the von Hippel-Lindau tumor suppressor protein.
Duan, D.R., Pause, A., Burgess, W.H., Aso, T., Chen, D.Y.T., Garrett, K.P., Conaway, R.C., Conaway, J.W., Linehan, W.M., and Klausner, R.D.
Science 269 1402-1406 1995-
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The RNA polymerase II elongation complex.
Aso, T., Conaway, J.W., and Conaway, R.C.
FASEB J. 9 1419-1428 1995-
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Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog.
Garrett, K.P., Aso, T., Bradsher, J.N., Foundling, S.I., Lane, W.S., Conaway, R.C., and Conaway, J.W.
Proc. Natl. Acad. Sci. U. S. A. 92 7172-7176 1995-
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A TATA sequence-dependent transcriptional repressor activity associated with mammalian transcription factor IIA.
Aso, T., Serizawa, H., Conaway, R.C., and Conaway, J.W.
EMBO J. 13 435-445 1994-
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Role of core promoter structure in assembly of the RNA polymerase II preinitiation complex.
Aso, T., Conaway, J.W., and Conaway, R.C.
J. Biol. Chem. 269 26575-26583 1994-
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Roles of both the RAP30 and RAP74 subunits of transcription factor IIF in transcription initiation and elongation by RNA polymerase II.
Tan, S., Aso, T., Conaway, R.C., and Conaway, J.W
J. Biol. Chem. 269 25684-25691 1994-
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Domain structure of a human general transcription initiation factor, TFIIF.
Yonaha, M., Aso, T., Kobayashi, Y., Vasavada, H., Yasukochi, Y., Weissman, S.M., and Kitajima, S.
Nucleic Acid Res. 21 273-279 1993-
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Assignment of the human GTF2F1 gene to chromosome 19p13.3.
Aso, T., Tsai, P., Kawaguchi, T., Menninger, J.C., Kitajima, S., Yasukochi, Y., Ward, D.C., and Weissman, S.M.
Genomics 16 252-253 1993-
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Characterization of cDNA for the large subunit of the transcription initiation factor TFIIF.
Aso, T., Vasavada, H., Kawaguchi, T., Germino, F.J., Ganguly, S., Kitajima, S., Weissman, S.M., and Yasukochi, Y.
Nature 355 461-464 1992-
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Genomic organization of the α-chain of the human C4b-binding protein gene.
Aso, T., Okamura, S., Matsuguchi, T., Sakamoto, N., Sata, T., and Niho, Y.
Biochem. Biophys. Res. Commun. 174 222-227 1991-
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Interleukin-6 and tumor necrosis factor alpha fully activate liver-specific gene expression of C4b-binding protein.
Matsuguchi, T., Okamura, S., Aso, T., Takahashi, K., and Niho, Y.
Biochem. Int. 23 979-985 1991-
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Molecular cloning of the cDNA coding for proline-rich protein (PRP) : identity of PRP as C4b-binding protein.
Matsuguchi, T., Okamura, S., Aso, T., Sata, T., and Niho, Y.
Biochem. Biophys. Res. Commun. 165 138-144 1989-
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