Osteocytes regulate osteoprotegerin expression via the p38-MAPK-CREB pathway in rheumatoid arthritis.
Keitaro Yasumoto;Toshifumi Fujiwara;Toshiaki Sugita;Shinkichi Arisumi;Shotaro Kawamura;Takeshi Utsunomiya;Daisuke Hara;Shinya Kawahara;Ryosuke Yamaguchi;Yukio Akasaki;Satoshi Hamai;Goro Motomura;Hisakata Yamada;Yasuharu Nakashima
JBMR plus 10 (4) ziag023-ziag0123 2026年4月1日 査読有り 研究論文（学術雑誌） 共著者
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Impact of orthopaedic surgery on quality of life in patients with rheumatoid arthritis: a retrospective study using the FRANK (Fukuoka rheumatoid arthritis Network) registry.
Tsurui R, Yamada H, Kondo M, Fukushi JI, Sakuraba K, Miyamura T, Ishida M, Nakamura M, Inoue Y, Tsuru T, Shuto T, Yoshizawa S, Ohishi M, Kamo K, Haraguchi A, Maeyama A, Ayano M, Akasaki Y, Fujiwara T, Hara D, Yamaguchi R, Arisumi S, Yasumoto K, Natori T, Sugita T, Niiro H, Nakashima Y.
Modern rheumatology 36 (2) 211-217 2026年3月5日 査読有り 研究論文（学術雑誌） 共著者
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Osteocytes regulate osteoprotegerin expression via the p38-MAPK-CREB pathway in rheumatoid arthritis
Yasumoto K, Fujiwara T, Sugita T, Arisumi S, Kawamura S, Utsunomiya T, Hara D, Kawahara S, Yamaguchi R, Akasaki Y, Hamai S, Motomura G, Yamada H, Nakashima Y
JBMR Plus 10 (4) ziag023-ziag023 2026年2月17日 査読有り 研究論文（学術雑誌） 共著者
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Non-B27 HLA-B alleles lack diagnostic value, necessitating composite clinical indices to distinguish axial spondyloarthritis from radiographic mimics in Japanese patients.
Yukio Akasaki;Toshifumi Fujiwara;Daisuke Hara;Ryosuke Yamaguchi;Ichiro Kurakazu;Keitaro Yasumoto;Takahiro Natori;Toshiaki Sugita;Shotaro Kawamura;Takahiro Inoue;Hisakata Yamada;Yasuharu Nakashima
Modern rheumatology 36 (1) 132-136 2025年7月29日 査読有り 研究論文（学術雑誌） 共著者
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Cluster analysis identifies the differential impact of disease activity and severity on functional status and patient satisfaction in rheumatoid arthritis: the FRANK registry.
Yukio Akasaki;Hisakata Yamada;Masakazu Kondo;Jun-Ichi Fukushi;Koji Sakuraba;Tomoya Miyamura;Motoko Ishida;Masataka Nakamura;Yasushi Inoue;Tomomi Tsuru;Toshihide Shuto;Seiji Yoshizawa;Masanobu Ohishi;Kenta Kamo;Akihisa Haraguchi;Akira Maeyama;Yojiro Arinobu;Hiroki Mitoma;Masahiro Ayano;Nobuyuki Ono;Toshifumi Fujiwara;Daisuke Hara;Ryosuke Yamaguchi;Ryosuke Tsurui;Keitaro Yasumoto;Takahiro Natori;Toshiaki Sugita;Hiroaki Niiro;Yasuharu Nakashima
Clinical and experimental rheumatology 43 (5) 861-866 2025年5月1日 査読有り 研究論文（学術雑誌） 共著者
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Characterization of patients with rheumatoid arthritis not using biologic/targeted synthetic disease-modifying drugs despite insufficient disease control: Another difficult-to-treat RA.
Hisakata Yamada;Ryosuke Tsurui;Masakazu Kondo;Jun-Ichi Fukushi;Koji Sakuraba;Tomoya Miyamura;Motoko Ishida;Masataka Nakamura;Yasushi Inoue;Tomomi Tsuru;Toshihide Shuto;Seiji Yoshizawa;Masanobu Ohishi;Kenta Kamo;Akihisa Haraguchi;Akiza Maeyama;Yojiro Arinobu;Hiroki Mitoma;Masahiro Ayano;Nobuyuki Ono;Yukio Akasaki;Toshifumi Fujiwara;Daisuke Hara;Shinkichi Arisumi;Keitaro Yasumoto;Takahiro Natori;Hiroaki Niiro;Yasuharu Nakashima
Modern rheumatology 35 (5) 830-836 2025年4月11日 査読有り 研究論文（学術雑誌） 共著者（筆頭）
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Risk factor analysis of vertebral fractures requiring surgery in patients with ankylosing spondylitis.
Kazuhiro Kai;Toshifumi Fujiwara;Yukio Akasaki;Hidetoshi Tsushima;Daisuke Hara;Shinkichi Arisumi;Ryosuke Tsurui;Keitaro Yasumoto;Hirokazu Saiwai;Kenichi Kawaguchi;Hisakata Yamada;Yasuharu Nakashima
Modern rheumatology 35 (1) 162-166 2024年12月25日 査読有り 研究論文（学術雑誌） 共著者
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Homeostatic signals, including IL-7 and self-MHC recognition, induce the development of peripheral helper T cells, which are enriched in the joints of rheumatoid arthritis.
Ryosuke Tsurui;Hisakata Yamada;Takahiro Natori;Motoki Yoshimura;Yukio Akasaki;Shinya Kawahara;Hiroaki Niiro;Yuya Kunisaki;Yasuharu Nakashima
Journal of translational autoimmunity 9 100258-100258 2024年12月1日 査読有り 研究論文（学術雑誌） 共著者
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Is there a reduction in hip destruction under a treat-to-target strategy in patients with rheumatoid arthritis?
Hidetoshi Tsushima;Sakuragi Takahide;Yukio Akasaki;Toshifumi Fujiwara;Daisuke Hara;Satoshi Ikemura;Kouji Sakuraba;Satoshi Kamura;Hisaaki Miyahara;Hisakata Yamada;Jun-Ichi Fukushi;Yasuharu Nakashima
Modern rheumatology 34 (2) 334-339 2024年2月26日 査読有り 研究論文（学術雑誌） 共著者
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Determination of the factors associated with antigen-specific CD4+ T-cell responses to BNT162b2 in patients with rheumatoid arthritis.
Fumiaki Sagawa;Hisakata Yamada;Masahiro Ayano;Yasutaka Kimoto;Hiroki Mitoma;Nobuyuki Ono;Yojiro Arinobu;Masakazu Kondo;Yasuharu Nakashima;Koichi Akashi;Takahiko Horiuchi;Hiroaki Niiro
RMD open 10 (1) e003693-e003693 2024年1月12日 査読有り 研究論文（学術雑誌） 共著者
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Synovial-tissue resident macrophages play proinflammatory functions in the pathogenesis of RA while maintaining the phenotypes in the steady state.
Kazuhiro Kai;Hisakata Yamada;Ryosuke Tsurui;Koji Sakuraba;Kenjiro Fujimura;Shinya Kawahara;Yukio Akasaki;Hidetoshi Tsushima;Toshifumi Fujiwara;Daisuke Hara;Jun-Ichi Fukushi;Shinichiro Sawa;Yasuharu Nakashima
Immunological medicine 47 (2) 1-10 2024年1月3日 査読有り 研究論文（学術雑誌） 共著者
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Low avidity observed for anti-citrullinated peptide antibody is not a general phenomenon for autoantibodies.
Hisakata Yamada;Akihisa Haraguchi;Tomomi Tsuru;Masakazu Kondo;Fumiaki Sagawa;Hiroaki Niiro;Yasuharu Nakashima
Annals of the rheumatic diseases 82 (12) 1637-1638 2023年12月1日 査読有り 研究論文（学術雑誌） 共著者（筆頭）
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Contributions of the N-terminal flanking residues of an antigenic peptide from the Japanese cedar pollen allergen Cry j 1 to the T-cell activation by HLA-DP5.
Seisuke Kusano;Sho Ueda;Daisuke Oryoji;Aya Toyoumi;Akiko Hashimoto-Tane;Hiroyuki Kishi;Hiroshi Hamana;Atsushi Muraguchi;Hui Jin;Hisashi Arase;Hiroko Miyadera;Reiko Kishikawa;Yasunobu Yoshikai;Hisakata Yamada;Ken Yamamoto;Yasuharu Nishimura;Takashi Saito;Takehiko Sasazuki;Shigeyuki Yokoyama
International immunology 35 (9) 447-458 2023年9月5日 査読有り 研究論文（学術雑誌） 共著者
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The Search for the Pathogenic T Cells in the Joint of Rheumatoid Arthritis: Which T-Cell Subset Drives Autoimmune Inflammation?
Hisakata Yamada
International journal of molecular sciences 24 (8) 6930-6941 2023年4月8日 査読有り 研究論文（学術雑誌） 単著者
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Adaptive immunity in the joint of rheumatoid arthritis.
Hisakata Yamada
Immunological medicine 45 (1) 1-11 2022年3月1日 査読有り 招待有り 研究論文（学術雑誌） 単著者
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Factors affecting patient satisfaction related to cost and treatment effectiveness in rheumatoid arthritis: results from the multicenter observational cohort study, FRANK Registry.
Toshifumi Fujiwara;Masakazu Kondo;Hisakata Yamada;Akihisa Haraguchi;Kenjiro Fujimura;Koji Sakuraba;Satoshi Kamura;Jun-Ichi Fukushi;Hisaaki Miyahara;Yasushi Inoue;Tomomi Tsuru;Toshihide Shuto;Seiji Yoshizawa;Eiichi Suematsu;Tomoya Miyamura;Masahiro Ayano;Hiroki Mitoma;Yojiro Arinobu;Hiroaki Niiro;Masanobu Ohishi;Akie Hirata;Shoji Tokunaga;Atsushi Takada;Daisuke Hara;Hidetoshi Tsushima;Yukio Akasaki;Satoshi Ikemura;Takuya Sueishi;Masakazu Toya;Takahide Sakuragi;Tomoko Tsutsui;Kazuhiro Kai;Shinkichi Arisumi;Yasuharu Nakashima
Arthritis research & therapy 24 (1) 53-53 2022年2月22日 研究論文（学術雑誌） 共著者
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G protein-coupled receptor kinase 5 deletion suppresses synovial inflammation in a murine model of collagen antibody-induced arthritis.
Masakazu Toya;Yukio Akasaki;Takuya Sueishi;Ichiro Kurakazu;Masanari Kuwahara;Taisuke Uchida;Tomoaki Tsutsui;Hidetoshi Tsushima;Hisakata Yamada;Martin K Lotz;Yasuharu Nakashima
Scientific reports 11 (1) 10481-10481 2021年5月18日 査読有り 研究論文（学術雑誌） 共著者
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Autoreactivity of Peripheral Helper T Cells in the Joints of Rheumatoid Arthritis.
Takahide Sakuragi;Hisakata Yamada;Akihisa Haraguchi;Kazuhiro Kai;Jun-Ichi Fukushi;Satoshi Ikemura;Yukio Akasaki;Toshifumi Fujiwara;Hidetoshi Tsushima;Tomoko Tsutsui;Masakazu Kondo;Yasunobu Yoshikai;Seiji Okada;Yasuharu Nakashima
J Immunol 206 (9) 2045-2051 2021年5月1日 査読有り 研究論文（学術雑誌） 共著者
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